St Augustine was the first one to think in the West, about time ... "What then is time? If no one asks me, I know what it is. If I wish to explain it to him who asks, I do not know." St Augustine was the first Heisenberg. This has been a theological question from the start, philosophical/secular explanations being the first step away from that. In theology space is also explained in theological terms. It was in the Middle Ages, that the first x vs t diagram was made to understand motion, even before Descartes (x vs y). This led to the absolute time and absolute space of Newton. This matched the theology of Newton (sensorium of God) which matched Plato.
But fact is it isn't quite accurate ... "Each observer has their own proper time measured by the clock in their rest frame. However, one man's proper time is not another man's proper time. Time dilation means that each observer will see the other observer's clock running slower (compared to their own proper time measuring clock)." aka Einstein. Which at the time was considered heresy by most physicists (except Mach). So already, even before Heisenberg, a person taking a measurement changes "reality". But "no hidden variables" quantum mechanics shows, that there is no such definite "reality" behind the measurement. There is only measurement. Plato was wrong.
Again, with polarizers, in my own room, I can demonstrate that Heisenberg is right. There is a quantum wave function, before measurement, but we can't know what its value is, unless we measure it. Much easier than trying to bounce a high energy photon off an electron (the usual example). This is part of a much more general mathematical problem, which impacts control theory (theory of automatic devices). In a mechanical system, you can't simultaneously control both position, velocity and acceleration (you can control any two). Because that would violate the definition of those variables.